The Prospective Association of Dietary Sugar Intake in Adolescence With Risk Markers of Type 2 Diabetes in Young Adulthood

Purpose: To examine the prospective relevance of dietary sugar intake (based on data as well urinary excretion data) in adolescent years for insulin sensitivity and biomarkers inflammation young adulthood. Methods: Overall 254 participants DONALD study who had at least two 3-day weighed records calculating intakes fructose, glucose, sucrose, total, free, added sugars, total sugars from sugar-sweetened beverages (SSB), juice, sweets/sugar or complete 24 h urine samples ( n = 221) (urinary fructose + sucrose) adolescence (females: 9–15 years, males: 10–16 years) a fasting blood sample adulthood (18–36 years), were included multivariable linear regression analyses assessing their associations with adult homeostasis model assessment (HOMA2-%S) pro-inflammatory score CRP, IL-6, IL-18, leptin, chemerin, adiponectin). Results: On level, no observed between added, sugar, SSB, juice HOMA2-%S p > 0.01). however, higher excreted levels associated improved 0.008) among females only. No Conclusion: The present did not provide support that consumed is sensitivity. one potential exception was moderate consumption which showed beneficial association